Institute for Precision Health
Publications
Take a look at publications by members of the Institute for Precision Health.
Chris Brightling
Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial.
PHOSP-COVID Collaborative Group. Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study.
Risankizumab in severe asthma – a phase 2a, placebo-controlled trial.
Effect of tezepelumab on airway inflammatory cells, remodelling, and hyperresponsiveness in patients with moderate-to-severe uncontrolled asthma (CASCADE): a double-blind, randomised, placebo-controlled, phase 2 trial.
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.
Jacqui Shaw
Tracking the Evolution of Non-Small-Cell Lung Cancer.
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
Personalized Detection of Circulating Tumor DNA Antedates Breast Cancer Metastatic Recurrence.
Prevalence of ctDNA in early screen-detected breast cancers using highly sensitive and specific dual molecular barcoded personalised mutation assays.
Circulating Tumor DNA Profiling From Breast Cancer Screening Through to Metastatic Disease.
Don Jones
Cov-MS: A Community-Based Template Assay for Mass-Spectrometry-Based Protein Detection in SARS-CoV-2 Patients.
Mass spectrometric detection of KRAS protein mutations using molecular imprinting.
Trimethylamine N-oxide and Risk Stratification after Acute Myocardial Infarction.
Modulation of acetylcholinesterase activity using molecularly imprinted polymer nanoparticles.
Plasma proteomic approach in patients with heart failure: insights into pathogenesis of disease progression and potential novel treatment targets.
Lynne Howells
Patient-derived explants (PDEs) as a powerful preclinical platform for anti-cancer drug and biomarker discovery.
Risk of cancer incidence and mortality associated with diabetes: A systematic review with trend analysis of 203 cohorts.
Curcumin Combined with FOLFOX Chemotherapy Is Safe and Tolerable in Patients with Metastatic Colorectal Cancer in a Randomized Phase IIa Trial.
Inequalities in cancer screening, prevention and service engagement between UK ethnic minority groups.
Evaluating and comparing immunostaining and computational methods for spatial profiling of drug response in patient-derived explants.